transLAB + n-D::StudioLab
United States
Where do you locate yourself in relation to the systems you work with?
Where are you heading, and what is pulling you there?
How would you describe the space your practice is currently unfolding in?
Description
Quantum Global Organoid Orchestra (qGOO) is an experimental art–science collaboration that links living neural tissue, generative media, and networked human participation to explore new forms of emergent creativity across species and systems. At its core are brain organoids—lab-grown clusters of neural cells cultivated in partnered neurobiology labs—which generate spontaneous electrical activity. This activity is recorded through high-density microelectrode arrays and translated in real time into sound, visual structures, and computational behaviors. In qGOO, organoids act as active “performers” within a hybrid ensemble of biological, human, and AI-driven processes. Their signals modulate generative algorithms that shape the audiovisual environment, while the resulting sensory field influences how audiences move, listen, and respond. The work thus operates as a closed-loop system of distributed cognition, where perception and agency are shared among living neural matter, machine interpretation, and human presence. Rather than presenting data as illustration, qGOO foregrounds sensation, emergence, and relationality. It invites reflection on the aesthetic and ethical implications of working with living neural material: what it means to position organoids—neither conventional subjects nor inert tools—as participants in an artistic system. By making the hidden rhythms of neural activity perceptible, the project proposes a speculative model of collective intelligence.
Process
qGOO grew out of an ongoing collaboration between transLAB and the Kosik Neurobiology Lab. Together, we began exploring how brain organoids, artificial intelligence, and human perception might form new kinds of immersive art–science systems—spaces where biological and computational intelligences intersect and influence one another in real time. The first outcome of this collaboration was "Protonoesis", exhibited at the NABI Art Center during ISEA 2025 in Seoul (credits: Nefeli Manoudaki, Iason Paterakis, Diarmid Flatley, Ryan Millett, Marcos Novak). The second, "Simulacra Naturae", was shown at die Angewandte, Vienna, for IEEE VISAP 2025 and will be exhibited at Currents New Media 2026 (credits: Nefeli Manoudaki, Mert Toka, Iason Paterakis, Diarmid Flatley, Stejara Iulia Dinulescu). Each iteration expanded our understanding of how organoid-driven systems shape sensory experience with living neural activity as a creative force. qGOO emerges as the next step: an effort to connect labs, artists, engineers, and scientists internationally, using brain organoid activity as a global real-time conductor. It is developed by the transLAB, nD::StudioLab, the Kosik Neurobiology Lab at UC Santa Barbara, and international collaborators including Marcos Novak, Mark-David Hosale, Iason Paterakis, Nefeli Manoudaki, Diarmid Flatley, Mert Toka, Ilze [Kavi] Briede, Marcus Gordon, Ken Kosik, Tjitse van der Molen, Alan Macy, Ken Fields, and composer Gene Coleman.
Tools
The work is built as a real-time, multi-layered A/V system. The core visual composition runs in TouchDesigner, with spatial audio composed and performed in Max/MSP. Brain organoid activity is streamed and analyzed by a custom JavaScript application, which extracts features from spike trains and sends control data to TouchDesigner and Max, orchestrating all layers of the installation in real-time. For generative elements, we used Stable Diffusion 2.1 within a distributed AI diffusion pipeline, and built control interfaces and simulations in React.js, JavaScript, Unity, and Processing. Networked communication across machines and locations relies on MQTT (via SHIFTR), which was crucial for keeping multiple visual layers synchronized at a final resolution of 10,560 × 2,160. The performance ran in two locations simultaneously: Toronto and Santa Barbara. The installation operates as a closed-loop system between brain organoid data and human biodata. During a live performance in Toronto, EEG signals from a performer—recorded with Biomeci’s "Source" device while she viewed the organoid spikes through custom-made glasses with LEDs—were sent back to the transLAB installation in Santa Barbara, modulating the evolving audiovisual composition and completing the feedback loop.
Imagine a few thousand brain organoids—neural cells, grown in a lab, never part of any consciousness—begin to fire. Spontaneously. Rhythmically. And somewhere in Santa Barbara and Toronto, sound and image emerge from that.
The Quantum Global Organoid Orchestra (qGOO) is one of those works that makes you stop and think: what the heck? Together with neurobiologists, transLAB and nD::StudioLab have built something that resists easy categorization—too alive for an installation, too artificial for nature, too collective for a single artwork. The electrical impulses of living cell clusters are translated in real time into sound, moving image, and spatial experience. The organoids transmit. The algorithms respond. Nobody conducts. Everything conducts.
What moves me about this work is not the technology alone. It’s the questions it raises without ever stating them: what is intelligence? What is expression? And what happens when we stop deciding who these concepts belong to?
Perhaps that’s what art can offer here: genuine wonder at what emerges when boundaries become permeable—between the living and the digital, between author and material, between laboratory and stage.





